New in Nature: Dr. Noé Brasier on applied body-fluid analysis by wearable devices.

Wearable devices enable constant and holistic health monitoring and analysis of physiological data in healthcare: How novel sensors analyse body fluids.

wearble devices

We are thrilled about the publication success in the nature portfolio of this innovative research work by Dr Noé Brasier, Early-Career Fellow, MedLab Fellow & General Internal Medicine, FMH. Noé is a Researcher at the Translational Science research Group, lead by Prof. Dr. Jörg Goldhahn, embedded in the Institute of Translational Medicine.  

Abstract:
Wearable sensors are a recent paradigm in healthcare, enabling continuous, decentralized, and non- or minimally invasive monitoring of health and disease. Continuous measurements yield information-rich time series of physiological data that are holistic and clinically meaningful. Although most wearable sensors were initially restricted to biophysical measurements, the next generation of wearable devices is now emerging that enable biochemical monitoring of both small and large molecules in a variety of body fluids, such as sweat, breath, saliva, tears and interstitial fluid.

Rapidly evolving data analysis and decision-making technologies through artificial intelligence has accelerated the application of wearables around the world. Although recent pilot trials have demonstrated the clinical applicability of these wearable devices, their widespread adoption will require large-scale validation across various conditions, ethical consideration and sociocultural acceptance. Successful translation of wearable devices from laboratory prototypes into clinical tools will further require a comprehensive transitional environment involving all stakeholders. The wearable device platforms must gain acceptance among different user groups, add clinical value for various medical indications, be eligible for reimbursements and contribute to public health initiatives. In this Perspective, we review state-of-the-art wearable devices for body-fluid analysis and their translation into clinical applications, and provide insight into their clinical purpose.

Read full nature article external page here

Brasier, N., Wang, J., Gao, W. et al. Applied body-fluid analysis by wearable devices. Nature 636, 57–68 (2024). https://doi.org/10.1038/s41586-024-08249-4

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